Antioxidant activity and sun screening effects of Bacterial melanin
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Date
2020-07-01
Journal Title
Journal ISSN
Volume Title
Publisher
Plovdiv University Press “Paisii Hilendarski”
Abstract
The present work was delineated to formulate and evaluate antioxidant and photoprotective properties of melanin produced by Pseudomonas mosselii strain STSGRDS1 against the purchased fungal melanin STSGRDM1 as standard. Initially, antioxidant assay were examined for the isolated bacterial melanin STSGRDS1 against the standard melanin STSGRDM1 that already have substantiated to have antioxidant ability by DPPH and ABTS, following with the detailed screening of radical scavenging activity were performed which includes valuation of peroxides, hydroxyl radicals, reduction potential and phosphomolybdenum method. This report depicts the antioxidant potential of the extracted melanin that could be further used as a potent antioxidant in scientific basis, as the percentage of free radical scavenging increased with increasing concentration of melanin. Study also signifies that bacterial melanin formulated creams had potency to protect against ultraviolet (UV) rays with sun protection factor (SPF) enhancement ranging from 1.95 to 26.06 and transmission spectroscopy revealed that the formulations has satisfied protection against UV A and UV B rays with good average UV A protection factor indicating sunscreen activity of the pigment. As a result, the isolated bacterial strain has immense photoprotection potential and radical scavenging activity that can be resorted in cosmetic formulations, UV protection devices, etc.
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Keywords
Melanin, Pseudomonas sp, antioxidant, SPF, Transmission spectroscopy