Immunomodulation of gastrointestinal tract by probiotics: an insight into the role of Lactobacillus sp. and Bacillus sp. on immunity

dc.contributor.authorD’Rose, Venetia
dc.contributor.authorBhat, Sarita G.
dc.date.accessioned2024-11-14T11:45:45Z
dc.date.available2024-11-14T11:45:45Z
dc.date.issued2023-07-23
dc.description.abstractThe gastrointestinal tract (GIT) is an immunologically active ecosystem with a crucial role in activating or stimulating the immune system as well as a barrier against microbial antigens. About a hundred trillion microorganisms such as bacteria, viruses, fungi, and protozoa cohabit with the GIT. Gut microbes play a vital role in health and disease, leading to the emergence of ‘probiotics’ a novel therapeutic consumption of live, beneficial cultures. Probiotics exhibit an extensive mechanism of action which include destroying/blocking pathogens, production of antimicrobial compounds, and modulation of the immune system without affecting intestinal homeostasis. Although Lactobacillus sp. is most abundantly used as a probiotic, reports also show the emergence of Bacillus sp. in boosting the immune system and promoting good health. This review attempts to highlight the potential of Lactobacillus and Bacillus species as a probiotic in stimulating the immune system.
dc.identifier.issn1314-6246
dc.identifier.urihttps://doi.uni-plovdiv.bg/handle/store/282
dc.language.isoen
dc.publisherPlovdiv University Press “Paisii Hilendarski”
dc.subjectProbiotics
dc.subjectLactobacillus
dc.subjectBacillus
dc.subjectImmune system
dc.subjectGastrointestinal tract
dc.titleImmunomodulation of gastrointestinal tract by probiotics: an insight into the role of Lactobacillus sp. and Bacillus sp. on immunity
dc.typeArticle
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